A hormone that stimulates the PITUITARY GLAND to secrete three hormones: gonadotrophic hormone (see GONADOTROPHINS), LUTEINISING HORMONE and FOLLICLE-STIMULATING HORMONE. Gonadorelin can be made artificially and given by intravenous injection. It is used to stimulate the OVARIES when treating infertile women, and to investigate suspected disease of the HYPOTHALAMUS. Analogues of the hormone (buserelin and goselerin) are chemically similar and can be used to suppress release of gonadorelin, so cutting the production of pituitary hormones. The two analogues are given to treat ENDOMETRIOSIS, breast cancer (see BREASTS, DISEASES OF) and prostate cancer (see PROSTATE GLAND, DISEASES OF).