Any disorder affecting the coagulability of blood (see COAGULATION). Among acute conditions precipitating the disorder are ABRUPTIO PLACENTAE, HAEMOLYSIS following blood transfusions, infection with GRAM-NEGATIVE BACTERIA, HEAT STROKE, SHOCK and snakebite. Chronic disorders linked with coagulopathy are septic ABORTION, TOXAEMIA of pregnancy, certain cancers and LEUKAEMIA.