A rare malignant growth of the retina (see EYE) which occurs in infants. It can sometimes be discovered at birth because shining a light in the baby's pupil produces a white reflection rather than a red one. Alternatively, the infant may present with a SQUINT. In 25 per cent of cases there is a family history of the condition and abnormality of chromosome 13 is common (see CHROMOSOMES). It is treated by removing the eye or, if affecting both eyes, by laser PHOTOCOAGULATION with or without RADIOTHERAPY.