An uncommon chronic inflammatory disease of unknown origin which can affect many organs, particularly the SKIN, eyes (see EYE) and LUNGS. It can first appear as ERYTHEMA nodosum with lymph-gland enlargement within the chest. In the eyes it causes UVEITIS. BIOPSY of affected tissue allows diagnosis, which is confirmed by a KVEIM TEST. Often sarcoidosis is self-limiting, but in severe cases oral CORTICOSTEROIDS may be needed.