A group of CYTOTOXIC drugs administered intravenously for the treatment of advanced ovarian cancer (see OVARIES, DISEASES OF) and secondary spread of breast cancer (see BREASTS, DISEASES OF). Given under specialist supervision in hospital, taxanes are not effective for all patients, but results are encouraging when they do respond. Side-effects include HYPERSENSITIVITY, MYELOSUPPRESSION, cardiac ARRHYTHMIA, and peripheral NEUROPATHY. Examples of the taxanes are PACLITAXEL and DOCETAXEL.